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Search Results for " anti-tumor immunity "

11

Compounds

Cat No. Product Name Synonyms Targets
T7611 ODM-203 VEGFR , FGFR
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
T77401 Bavituximab Anti-PS MAb 3G4 Others
Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a monoclonal antibody against phosphatidylserine (PS) with vascular targeting and immunomodulatory properties. It can reactivate anti-tumor immunity to ...
T3S1513 (20R)-Protopanaxadiol Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol Others , Antibacterial
1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...
T61248 HDAC-IN-32
HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells...
T82043 Iso5-2DC18
Iso5-2DC18, a lipid, is utilized in the synthesis of amine-containing lipids, which are instrumental in mRNA delivery, activation of the stimulator of interferon genes (STING) pathway, and demonstration of anti-tumor imm...
T63329 PD-1/PD-L1-IN-25
PD-1/PD-L1-IN-25 is an inhibitor of PD-1/PD-L1 interaction (IC50: 16.17 nM) that effectively activates anti-tumor immunity of T cells in PBMCs. PD-1/PD-L1-IN-25 can be used to study cancer.
T79635 LYP-IN-4 Phosphatase
LYP-IN-4 (compound D14), a reversible and selective lymphotyrosine phosphatase (LYP) inhibitor (Ki=1.34 μM, IC50=3.52μM), regulates TCR signaling, increases PD-1/PD-L1 expression, and strengthens anti-tumor immunity. It ...
T63553 HPK1-IN-28
HPK1-IN-28 is a potent inhibitor of HPK1, a negative regulator of dendritic cell (DC), T-cell and B-cell activation responses. HPK1-IN-28 is effective in enhancing anti-tumor immunity in humans and has shown research pot...
T63270 HPK1-IN-29
HPK1-IN-29 is a potent inhibitor of HPK1, in which hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 is able to enhance ...
T77052 Latikafusp
Latikafusp (AMG 256), a bifunctional fusion protein, combines a PD-1-targeting antibody with an IL-21 mutein, facilitating IL-21 pathway stimulation in PD-1+ cells. It aims to enhance and sustain the functionality of cyt...
T35573 Adenosine 5’-methylenediphosphate (hydrate)
Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or ...
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